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Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
Transforming growth factor β (TGFβ) is one of few known negative regulators of hematopoiesis, yet the mechanisms by which it affects cell cycle arrest and stem cell quiescence are poorly understood. Induction of the cyclin-dependent kinase inhibitors, p15INK4b (p15) and p21WAF1 (p21) is important fo...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15477587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406771101 |
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