Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia

INTRODUCTION: TRPM2 channels have been suggested to play a role in ischemic neuronal injury, specifically in males. A major hindrance to TRPM2 research has been the lack of specific TRPM2 inhibitors. The current study characterized the specificity and neuroprotective efficacy of a novel TRPM2 inhibi...

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Publicado no:Exp Neurol
Main Authors: Shimizu, Takeru, Dietz, Robert M., Cruz-Torres, Ivelisse, Strnad, Frank, Garske, Ana K., Moreno, Myriam, Venna, Venugopal R., Quillinan, Nidia, Herson, Paco S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240152/
https://ncbi.nlm.nih.gov/pubmed/27317297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.06.015
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