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Reversal of global ischemia-induced cognitive dysfunction by delayed inhibition of TRPM2 ion channels

Hippocampal injury and cognitive impairments are common after cardiac arrest and stroke and do not have an effective intervention despite much effort. Therefore we developed a new approach aimed at reversing synaptic dysfunction by targeting TRPM2 channels. Cardiac arrest/cardiopulmonary resuscitati...

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Bibliographic Details
Published in:Transl Stroke Res
Main Authors: Dietz, Robert M., Cruz-Torres, Ivelisse, Orfila, James E., Patsos, Olivia P., Shimizu, Kaori, Chalmers, Nicholas, Deng, Guiying, Tiemeier, Erika, Quillinan, Nidia, Herson, Paco S.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934940/
https://ncbi.nlm.nih.gov/pubmed/31250378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-019-00712-z
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