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Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma.

We detected a germ-line mutation of the p53 gene in a patient with a malignant ependymoma of the posterior fossa. This mutation, which was found at codon 242, resulted in an amino acid substitution in a highly conserved site of exon 7 of the p53 gene; the same mutation was found in both the germ-lin...

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書誌詳細
主要な著者: Metzger, A K, Sheffield, V C, Duyk, G, Daneshvar, L, Edwards, M S, Cogen, P H
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC52396/
https://ncbi.nlm.nih.gov/pubmed/1679237
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