Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma.
We detected a germ-line mutation of the p53 gene in a patient with a malignant ependymoma of the posterior fossa. This mutation, which was found at codon 242, resulted in an amino acid substitution in a highly conserved site of exon 7 of the p53 gene; the same mutation was found in both the germ-lin...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52396/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1679237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7825 |
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