Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis
Ectopic expression of decorin in a wide variety of transformed cells results in growth arrest and the inability to generate tumors in nude mice. This process is caused by a decorin-mediated activation of the epidermal growth factor receptor, which leads to a sustained induction of endogenous p21(WAF...
Kaydedildi:
| Yayımlandı: | Proc Natl Acad Sci U S A |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1999
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.3092 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|