Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator

[Image: see text] Development of orally bioavailable nonsteroidal selective estrogen receptor downregulators (SERDs) provides clinical opportunities for the long-term treatment and adjuvant therapy of breast cancer at all stages. We describe the design, synthesis, and identification of a boron-modif...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Med Chem Lett
मुख्य लेखकों: Liu, Jiawang, Zheng, Shilong, Guo, Shanchun, Zhang, Changde, Zhong, Qiu, Zhang, Qiang, Ma, Peng, Skripnikova, Elena V., Bratton, Melyssa R., Wiese, Thomas E., Wang, Guangdi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2016
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238461/
https://ncbi.nlm.nih.gov/pubmed/28105283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00410
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