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GLL398, an Oral Selective Estrogen Receptor Degrader (SERD), Blocks Tumor Growth in Xenograft Breast Cancer Models

PURPOSE: Selective estrogen receptor degrader (SERD) has proven clinically effective in treating advanced or metastatic breast cancer since the approval of fulvestrant by FDA in 2002. Recent expansion of indications as a first line monotherapy and as combination therapy with CDK4/6 inhibitors furthe...

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Publicat a:Breast Cancer Res Treat
Autors principals: Guo, Shanchun, Zhang, Changde, Mottamal, Madhusoodanan, Hossain, Ahamed, Liu, Jiawang, Wang, Guangdi
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069796/
https://ncbi.nlm.nih.gov/pubmed/32030569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05558-w
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