The release and trans-synaptic transmission of Tau via exosomes

BACKGROUND: Tau pathology in AD spreads in a hierarchical pattern, whereby it first appears in the entorhinal cortex, then spreads to the hippocampus and later to the surrounding areas. Based on this sequential appearance, AD can be classified into six stages (“Braak stages”). The mechanisms and age...

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Bibliografische gegevens
Gepubliceerd in:Mol Neurodegener
Hoofdauteurs: Wang, Yipeng, Balaji, Varun, Kaniyappan, Senthilvelrajan, Krüger, Lars, Irsen, Stephan, Tepper, Katharina, Chandupatla, RamReddy, Maetzler, Walter, Schneider, Anja, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237256/
https://ncbi.nlm.nih.gov/pubmed/28086931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0143-y
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