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Reduced beta 2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme.
We have generated three artificial hammerhead ribozymes, denoted 'Rz-b', 'Rz-c' and 'Rz-d', with different specificities for exon II of the mouse beta-2-microglobulin (beta 2M) mRNA. In this study we tested for ribozyme mediated reduction of beta 2M mRNA in a cell line...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1994
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523680/ https://ncbi.nlm.nih.gov/pubmed/8036151 |
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