Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
The sequences surrounding the first 5'GUC3' in the mRNA encoding the Alzheimer amyloid peptide precursor (beta APP) were used to construct a pair of transacting hammerhead ribozymes. Each ribozyme contained the conserved core bases of the hammerhead motif found in the positive strand of satellite RN...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8371986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.17.4119 |
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