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Cleavage of full-length beta APP mRNA by hammerhead ribozymes.

The sequences surrounding the first 5'GUC3' in the mRNA encoding the Alzheimer amyloid peptide precursor (beta APP) were used to construct a pair of transacting hammerhead ribozymes. Each ribozyme contained the conserved core bases of the hammerhead motif found in the positive strand of sa...

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Hlavní autor: Denman, R B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310017/
https://ncbi.nlm.nih.gov/pubmed/8371986
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