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Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

Hematopoietic stem cells (HSCs) sustain blood formation throughout life. Pathways regulating maintenance of adult HSCs are largely unknown. Here we report that the Ets-related transcription factor Tel/Etv6, the product of a locus frequently involved in translocations in leukemia, is a selective regu...

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Autors principals: Hock, Hanno, Meade, Eliza, Medeiros, Sarah, Schindler, Jeffrey W., Valk, Peter J.M., Fujiwara, Yuko, Orkin, Stuart H.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC522982/
https://ncbi.nlm.nih.gov/pubmed/15371326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1239604
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