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Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

Hematopoietic stem cells (HSCs) sustain blood formation throughout life. Pathways regulating maintenance of adult HSCs are largely unknown. Here we report that the Ets-related transcription factor Tel/Etv6, the product of a locus frequently involved in translocations in leukemia, is a selective regu...

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Detalhes bibliográficos
Main Authors: Hock, Hanno, Meade, Eliza, Medeiros, Sarah, Schindler, Jeffrey W., Valk, Peter J.M., Fujiwara, Yuko, Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522982/
https://ncbi.nlm.nih.gov/pubmed/15371326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1239604
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