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Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

Hematopoietic stem cells (HSCs) sustain blood formation throughout life. Pathways regulating maintenance of adult HSCs are largely unknown. Here we report that the Ets-related transcription factor Tel/Etv6, the product of a locus frequently involved in translocations in leukemia, is a selective regu...

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Autori principali: Hock, Hanno, Meade, Eliza, Medeiros, Sarah, Schindler, Jeffrey W., Valk, Peter J.M., Fujiwara, Yuko, Orkin, Stuart H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC522982/
https://ncbi.nlm.nih.gov/pubmed/15371326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1239604
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