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Reduced Erg dosage impairs survival of hematopoietic stem and progenitor cells

ERG, an ETS family transcription factor frequently overexpressed in human leukemia, has been implicated as a key regulator of hematopoietic stem cells. However, how ERG controls normal hematopoiesis, particularly at the stem and progenitor cell level, and how it contributes to leukemogenesis remain...

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Podrobná bibliografie
Vydáno v:Stem Cells
Hlavní autoři: Xie, Ying, Koch, Mia Lee, Zhang, Xin, Hamblen, Melanie J., Godinho, Frank J., Fujiwara, Yuko, Xie, Huafeng, Klusmann, Jan-Henning, Orkin, Stuart H., Li, Zhe
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532742/
https://ncbi.nlm.nih.gov/pubmed/28436588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2627
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