miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

Children with trisomy 21/Down syndrome (DS) are at high risk to develop acute megakaryoblastic leukemia (DS-AMKL) and the related transient leukemia (DS-TL). The factors on human chromosome 21 (Hsa21) that confer this predisposing effect, especially in synergy with consistently mutated transcription...

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Detalhes bibliográficos
Main Authors: Klusmann, Jan-Henning, Li, Zhe, Böhmer, Katarina, Maroz, Aliaksandra, Koch, Mia Lee, Emmrich, Stephan, Godinho, Frank J., Orkin, Stuart H., Reinhardt, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827843/
https://ncbi.nlm.nih.gov/pubmed/20194440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1856210
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