LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia

BACKGROUND: Long non-coding RNAs (lncRNAs) are recognized as pivotal players during developmental ontogenesis and pathogenesis of cancer. The intronic microRNA (miRNA) clusters miR-99a ~ 125b-2 and miR-100 ~ 125b-1 promote progression of acute megakaryoblastic leukemia (AMKL), an aggressive form of...

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Main Authors: Emmrich, Stephan, Streltsov, Alexandra, Schmidt, Franziska, Thangapandi, Veera Raghavan, Reinhardt, Dirk, Klusmann, Jan-Henning
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118279/
https://ncbi.nlm.nih.gov/pubmed/25027842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-171
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