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Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
Centrosomes are the principal microtubule organising centres in somatic cells. Abnormal centrosome number is common in tumours and occurs after γ-irradiation and in cells with mutations in DNA repair genes. To investigate how DNA damage causes centrosome amplification, we examined cells that conditi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522792/ https://ncbi.nlm.nih.gov/pubmed/15359281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600393 |
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