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The controlling role of ATM in homologous recombinational repair of DNA damage

The human genetic disorder ataxia telangiectasia (A–T), caused by mutation in the ATM gene, is characterized by chromosomal instability, radiosensitivity and defective cell cycle checkpoint activation. DNA double-strand breaks (dsbs) persist in A–T cells after irradiation, but the underlying defect...

詳細記述

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書誌詳細
出版年:EMBO J
主要な著者: Morrison, Ciaran, Sonoda, Eiichiro, Takao, Noriaki, Shinohara, Akira, Yamamoto, Ken-ichi, Takeda, Shunichi
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10654944/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.3.463
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