A novel isoflavone, ME-344, targets the cytoskeleton in acute myeloid leukemia

The isoflavone ME-344 is a potent anti-cancer agent with preclinical and clinical efficacy in solid tumors. Yet, the mechanism of action of ME-344 has not been fully defined and the preclinical efficacy in leukemia has not been established. Therefore, we investigated the anti-leukemic properties and...

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Publicado en:Oncotarget
Autores principales: Jeyaraju, Danny V., Hurren, Rose, Wang, Xiaoming, MacLean, Neil, Gronda, Marcela, Shamas-Din, Aisha, Minden, Mark D., Giaever, Guri, Schimmer, Aaron D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226547/
https://ncbi.nlm.nih.gov/pubmed/27391350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10446
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