A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation. Blocking mitochondrial protein synthesis through genetic and chemical approaches kills human AML cells at all stages o...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Reed, Gregory A., Schiller, Gary J., Kambhampati, Suman, Tallman, Martin S., Douer, Dan, Minden, Mark D., Yee, Karen W., Gupta, Vikas, Brandwein, Joseph, Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Shamas‐Din, Aisha, Schuh, Andre C., Schimmer, Aaron D.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Clinical Cancer Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119957/
https://ncbi.nlm.nih.gov/pubmed/27734609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.845
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