A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation. Blocking mitochondrial protein synthesis through genetic and chemical approaches kills human AML cells at all stages o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Med
Egile Nagusiak: Reed, Gregory A., Schiller, Gary J., Kambhampati, Suman, Tallman, Martin S., Douer, Dan, Minden, Mark D., Yee, Karen W., Gupta, Vikas, Brandwein, Joseph, Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Shamas‐Din, Aisha, Schuh, Andre C., Schimmer, Aaron D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Clinical Cancer Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119957/
https://ncbi.nlm.nih.gov/pubmed/27734609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.845
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