A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation. Blocking mitochondrial protein synthesis through genetic and chemical approaches kills human AML cells at all stages o...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Reed, Gregory A., Schiller, Gary J., Kambhampati, Suman, Tallman, Martin S., Douer, Dan, Minden, Mark D., Yee, Karen W., Gupta, Vikas, Brandwein, Joseph, Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Shamas‐Din, Aisha, Schuh, Andre C., Schimmer, Aaron D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119957/
https://ncbi.nlm.nih.gov/pubmed/27734609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.845
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