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Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations

Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Neuwald, Andrew F., Altschul, Stephen F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225019/
https://ncbi.nlm.nih.gov/pubmed/28002465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005294
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