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Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers
Aptamers directed against human thrombin can selectively bind to two different exosites on the protein surface. The simultaneous use of two DNA aptamers, HD1 and HD22, directed to exosite I and exosite II respectively, is a very powerful approach to exploit their combined affinity. Indeed, strategie...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224481/ https://ncbi.nlm.nih.gov/pubmed/27899589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1113 |
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