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Thrombin binding aptamer G-quadruplex stabilized by pyrene-modified nucleotides
Guanine-rich regions of the human genome can adopt non-canonical secondary structures. Their role in regulating gene expression has turned them into promising targets for therapeutic intervention. Ligands based on polyaromatic moieties are especially suitable for targeting G-quadruplexes utilizing t...
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| I publikationen: | Nucleic Acids Res |
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| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144916/ https://ncbi.nlm.nih.gov/pubmed/32095808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa118 |
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