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Additive-Free Pd-Catalyzed α-Allylation of Imine-Containing Heterocycles

[Image: see text] An additive-free Pd-catalyzed α-allylation of different imino-group-ontaining heterocycles is reported. The activation of α-CH pronucleophiles (pK(a) (DMSO) > 25) occurs without the addition of strong bases or Lewis acids using only the Pd/Xantphos catalyst system. The reaction...

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Publicat a:Org Lett
Autors principals: Kljajic, Marko, Puschnig, Johannes G., Weber, Hansjörg, Breinbauer, Rolf
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223276/
https://ncbi.nlm.nih.gov/pubmed/27936786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b03407
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