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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Fujiwara, Tomohiro, Ozaki, Toshifumi
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223039/
https://ncbi.nlm.nih.gov/pubmed/28115942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2603092
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