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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Bibliografische gegevens
Gepubliceerd in:Stem Cells Int
Hoofdauteurs: Fujiwara, Tomohiro, Ozaki, Toshifumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223039/
https://ncbi.nlm.nih.gov/pubmed/28115942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2603092
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