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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Bibliografiska uppgifter
I publikationen:Stem Cells Int
Huvudupphovsmän: Fujiwara, Tomohiro, Ozaki, Toshifumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223039/
https://ncbi.nlm.nih.gov/pubmed/28115942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2603092
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