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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Fujiwara, Tomohiro, Ozaki, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223039/
https://ncbi.nlm.nih.gov/pubmed/28115942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2603092
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