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Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells

Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. Recent progress in their multimodal treatment has gradually improved patient prognosis; however, drug resistance and distant metastasis remain unresolved clinical problems. Recent inves...

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Vydáno v:Stem Cells Int
Hlavní autoři: Fujiwara, Tomohiro, Ozaki, Toshifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223039/
https://ncbi.nlm.nih.gov/pubmed/28115942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2603092
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