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Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still poorly understood. Using purified yeast replication proteins and fully chromatinized templates, we have reconstituted this process in vitro. We show that chromatin enforces DNA r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Kurat, Christoph F., Yeeles, Joseph T.P., Patel, Harshil, Early, Anne, Diffley, John F.X.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222724/
https://ncbi.nlm.nih.gov/pubmed/27989438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.016
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