Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium

Aberrant Wnt signaling within breast cancer is associated with poor prognosis, but regulation of this pathway in breast tissue remains poorly understood and the consequences of immediate or long-term dysregulation remain elusive. The exact contribution of the Wnt-regulating proteins adenomatous poly...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Daly, C S, Shaw, P, Ordonez, L D, Williams, G T, Quist, J, Grigoriadis, A, Van Es, J H, Clevers, H, Clarke, A R, Reed, K R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219933/
https://ncbi.nlm.nih.gov/pubmed/27694902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.342
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