Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis

Many components of Wnt/β-catenin signaling pathway also play critical roles in mammary tumor development, yet the role of the tumor suppressor gene APC (adenomatous polyposis coli) in breast oncongenesis is unclear. To better understand the role of Apc in mammary tumorigenesis, we introduced conditi...

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Bibliographic Details
Main Authors: Kuraguchi, Mari, Ohene-Baah, Nana Yaw, Sonkin, Dmitriy, Bronson, Roderick Terry, Kucherlapati, Raju
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629572/
https://ncbi.nlm.nih.gov/pubmed/19197353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000367
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