Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium

Aberrant Wnt signaling within breast cancer is associated with poor prognosis, but regulation of this pathway in breast tissue remains poorly understood and the consequences of immediate or long-term dysregulation remain elusive. The exact contribution of the Wnt-regulating proteins adenomatous poly...

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Veröffentlicht in:Oncogene
Hauptverfasser: Daly, C S, Shaw, P, Ordonez, L D, Williams, G T, Quist, J, Grigoriadis, A, Van Es, J H, Clevers, H, Clarke, A R, Reed, K R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219933/
https://ncbi.nlm.nih.gov/pubmed/27694902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.342
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