RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Deregulation of the Wnt/APC/β-catenin signaling pathway is an important consequence of tumor suppressor APC dysfunction. Genetic and molecular data have established that disruption of this pathway contributes to the development of colorectal cancer. Here, we demonstrate that the transcriptional core...

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Bibliografski detalji
Glavni autori: Lapierre, Marion, Bonnet, Sandrine, Bascoul-Mollevi, Caroline, Ait-Arsa, Imade, Jalaguier, Stéphan, Del Rio, Maguy, Plateroti, Michela, Roepman, Paul, Ychou, Marc, Pannequin, Julie, Hollande, Frédéric, Parker, Malcolm, Cavailles, Vincent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001527/
https://ncbi.nlm.nih.gov/pubmed/24667635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65178
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