RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Deregulation of the Wnt/APC/β-catenin signaling pathway is an important consequence of tumor suppressor APC dysfunction. Genetic and molecular data have established that disruption of this pathway contributes to the development of colorectal cancer. Here, we demonstrate that the transcriptional core...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lapierre, Marion, Bonnet, Sandrine, Bascoul-Mollevi, Caroline, Ait-Arsa, Imade, Jalaguier, Stéphan, Del Rio, Maguy, Plateroti, Michela, Roepman, Paul, Ychou, Marc, Pannequin, Julie, Hollande, Frédéric, Parker, Malcolm, Cavailles, Vincent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001527/
https://ncbi.nlm.nih.gov/pubmed/24667635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65178
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