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Correlation between In Vitro Susceptibility of Scedosporium apiospermum to Voriconazole and In Vivo Outcome of Scedosporiosis in Guinea Pigs
We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Scedosporium apiospermum in immunodepressed guinea pigs. Animals were infected with two strains; one required a VRC MIC of 0.5 to 1 μg/ml, common for this fungus, and the other required a high MIC (8 μg/ml), unusual in t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521912/ https://ncbi.nlm.nih.gov/pubmed/15388467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4009-4011.2004 |
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