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Correlation between In Vitro Susceptibility of Scedosporium apiospermum to Voriconazole and In Vivo Outcome of Scedosporiosis in Guinea Pigs

We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Scedosporium apiospermum in immunodepressed guinea pigs. Animals were infected with two strains; one required a VRC MIC of 0.5 to 1 μg/ml, common for this fungus, and the other required a high MIC (8 μg/ml), unusual in t...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Capilla, Javier, Guarro, Josep
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521912/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.4009-4011.2004
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