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Efficacy of Voriconazole in Treatment of Systemic Scedosporiosis in Neutropenic Mice
We have evaluated the efficacy of voriconazole (VRC) in a murine model of systemic infection by Scedosporium apiospermum. The survival of mice treated with VRC at 5, 20, or 40 mg/kg/day was greater than that of the control group (P ≤ 0.0009). VRC reduced the tissue burden in the spleen and brain (P...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC296198/ https://ncbi.nlm.nih.gov/pubmed/14638514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3976-3978.2003 |
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