Efficacy of Voriconazole in Treatment of Systemic Scedosporiosis in Neutropenic Mice

We have evaluated the efficacy of voriconazole (VRC) in a murine model of systemic infection by Scedosporium apiospermum. The survival of mice treated with VRC at 5, 20, or 40 mg/kg/day was greater than that of the control group (P ≤ 0.0009). VRC reduced the tissue burden in the spleen and brain (P...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Capilla, Javier, Serena, Carolina, Pastor, F. Javier, Ortoneda, Montserrat, Guarro, Josep
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3976-3978.2003
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