Efficacy of Voriconazole in Treatment of Systemic Scedosporiosis in Neutropenic Mice
We have evaluated the efficacy of voriconazole (VRC) in a murine model of systemic infection by Scedosporium apiospermum. The survival of mice treated with VRC at 5, 20, or 40 mg/kg/day was greater than that of the control group (P ≤ 0.0009). VRC reduced the tissue burden in the spleen and brain (P...
Spremljeno u:
| Izdano u: | Antimicrob Agents Chemother |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2003
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3976-3978.2003 |
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