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Efficacy of Amphotericin B at Suboptimal Dose Combined with Voriconazole in a Murine Model of Aspergillus fumigatus Infection with Poor In Vivo Response to the Azole

The combination of amphotericin B at a suboptimal dose (0.3 mg/kg) with voriconazole has shown efficacy in prolonging survival and reducing tissue burden in a murine model of disseminated infection by an isolate of Aspergillus fumigatus that had showed a poor in vivo response to the azole. The effic...

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Détails bibliographiques
Auteurs principaux: Sandoval-Denis, Marcelo, Pastor, F. Javier, Capilla, Javier, Guarro, Josep
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754337/
https://ncbi.nlm.nih.gov/pubmed/23796928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00563-13
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