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MIC Values of Voriconazole Are Predictive of Treatment Results in Murine Infections by Aspergillus terreus Species Complex

We evaluated the efficacy of voriconazole against nine strains of Aspergillus terreus with different MICs (0.12 to 4 μg/ml) by using a murine model. Markers of efficacy included survival, tissue burden, galactomannan antigenemia, and drug serum levels. Voriconazole was especially effective in prolon...

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Detalhes bibliográficos
Main Authors: Salas, Valentina, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Mayayo, Emilio, Fothergill, Annette W., Rinaldi, Michael G., Guarro, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591889/
https://ncbi.nlm.nih.gov/pubmed/23295929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01436-12
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