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MIC Values of Voriconazole Are Predictive of Treatment Results in Murine Infections by Aspergillus terreus Species Complex

We evaluated the efficacy of voriconazole against nine strains of Aspergillus terreus with different MICs (0.12 to 4 μg/ml) by using a murine model. Markers of efficacy included survival, tissue burden, galactomannan antigenemia, and drug serum levels. Voriconazole was especially effective in prolon...

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Главные авторы: Salas, Valentina, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Mayayo, Emilio, Fothergill, Annette W., Rinaldi, Michael G., Guarro, Josep
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591889/
https://ncbi.nlm.nih.gov/pubmed/23295929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01436-12
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