In Vitro and In Vivo Activities of Posaconazole and Amphotericin B in a Murine Invasive Infection by Mucor circinelloides: Poor Efficacy of Posaconazole

The in vitro susceptibility of 17 strains of Mucor circinelloides to amphotericin B and posaconazole was ascertained by using broth microdilution and disk diffusion methods and by determining the minimal fungicidal concentration (MFC). We evaluated the efficacy of posaconazole at 40 mg/kg of body we...

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Hauptverfasser: Salas, Valentina, Pastor, F. Javier, Calvo, Enrique, Alvarez, Eduardo, Sutton, Deanna A., Mayayo, Emilio, Fothergill, Anette W., Rinaldi, Michael G., Guarro, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346623/
https://ncbi.nlm.nih.gov/pubmed/22290952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05956-11
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