Correlation of In Vitro Activity, Serum Levels, and In Vivo Efficacy of Posaconazole against Rhizopus microsporus in a Murine Disseminated Infection

A broth microdilution method was used to evaluate the in vitro activities of seven antifungal agents against 15 clinical strains of Rhizopus microsporus. Amphotericin B (AMB) and posaconazole (POS) were the most active drugs. In a model of disseminated R. microsporus infection in immunosuppressed mi...

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Hlavní autoři: Rodríguez, M. Mar, Pastor, F. Javier, Calvo, Enrique, Salas, Valentina, Sutton, Deanna A., Guarro, Josep
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786372/
https://ncbi.nlm.nih.gov/pubmed/19786601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01026-09
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