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Posaconazole Combined with Amphotericin B, an Effective Therapy for a Murine Disseminated Infection Caused by Rhizopus oryzae

In a murine model of disseminated zygomycosis, low doses of amphotericin B (0.3 mg/kg body weight/day) combined with posaconazole (40 mg/kg/day) prolonged survival and reduced tissue burden with respect to that of controls and that of both drugs administered alone. Results were similar to those obta...

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Detalhes bibliográficos
Main Authors: Rodríguez, M. Mar, Serena, Carolina, Mariné, Marçal, Pastor, F. Javier, Guarro, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565887/
https://ncbi.nlm.nih.gov/pubmed/18694953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00628-08
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