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Efficacy of Posaconazole in a Murine Disseminated Infection by Candida tropicalis
We evaluated the efficacy of posaconazole against Candida tropicalis in a systemic infection model with immunosuppressed mice. Posaconazole at 50 mg/kg of body weight/day prolonged the survival of mice and reduced the fungal tissue burden of mice infected with any of the five strains tested, with th...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798508/ https://ncbi.nlm.nih.gov/pubmed/19841151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01136-09 |
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