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Efficacy of Posaconazole in a Murine Disseminated Infection by Candida tropicalis

We evaluated the efficacy of posaconazole against Candida tropicalis in a systemic infection model with immunosuppressed mice. Posaconazole at 50 mg/kg of body weight/day prolonged the survival of mice and reduced the fungal tissue burden of mice infected with any of the five strains tested, with th...

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Detalhes bibliográficos
Main Authors: Mariné, Marçal, Pastor, F. Javier, Guarro, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798508/
https://ncbi.nlm.nih.gov/pubmed/19841151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01136-09
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