Activities of Flucytosine, Fluconazole, Amphotericin B, and Micafungin in a Murine Model of Disseminated Infection by Candida glabrata

We compared the efficacies of amphotericin B, fluconazole, flucytosine, and micafungin in a systemic murine infection by three isolates of Candida glabrata. Amphotericin B showed the best results, although none of the drugs dramatically reduced mortality or tissue burden in liver or spleen.

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Bibliographic Details
Main Authors: Mariné, Marçal, Serena, Carolina, Fernández-Torres, Belkys, Pastor, F. Javier, Guarro, Josep
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280170/
https://ncbi.nlm.nih.gov/pubmed/16251323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4757-4759.2005
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