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MIC Values of Voriconazole Are Predictive of Treatment Results in Murine Infections by Aspergillus terreus Species Complex

We evaluated the efficacy of voriconazole against nine strains of Aspergillus terreus with different MICs (0.12 to 4 μg/ml) by using a murine model. Markers of efficacy included survival, tissue burden, galactomannan antigenemia, and drug serum levels. Voriconazole was especially effective in prolon...

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Main Authors: Salas, Valentina, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Mayayo, Emilio, Fothergill, Annette W., Rinaldi, Michael G., Guarro, Josep
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591889/
https://ncbi.nlm.nih.gov/pubmed/23295929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01436-12
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