MIC Values of Voriconazole Are Predictive of Treatment Results in Murine Infections by Aspergillus terreus Species Complex

We evaluated the efficacy of voriconazole against nine strains of Aspergillus terreus with different MICs (0.12 to 4 μg/ml) by using a murine model. Markers of efficacy included survival, tissue burden, galactomannan antigenemia, and drug serum levels. Voriconazole was especially effective in prolon...

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Bibliographische Detailangaben
Hauptverfasser: Salas, Valentina, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Mayayo, Emilio, Fothergill, Annette W., Rinaldi, Michael G., Guarro, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591889/
https://ncbi.nlm.nih.gov/pubmed/23295929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01436-12
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