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Efficacy of Voriconazole in a Guinea Pig Model of Invasive Trichosporonosis

We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Trichosporon asahii in immunosuppressed guinea pigs. VRC was more effective than amphotericin B in prolonging survival and reducing tissue burden. The best results were obtained with VRC at 10 mg/kg of body weight/day.

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Autors principals: Serena, Carolina, Gilgado, Félix, Mariné, Marçal, Pastor, F. Javier, Guarro, Josep
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479129/
https://ncbi.nlm.nih.gov/pubmed/16723595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00045-06
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